Lentiviral Vectors Mediate Long-Term and High Efficiency Transgene Expression in HEK 293T cells
نویسندگان
چکیده
منابع مشابه
Lentiviral Vectors Mediate Long-Term and High Efficiency Transgene Expression in HEK 293T cells
OBJECTIVES Lentiviral vectors have been used successfully to rapidly produce decigram quantities of active recombinant proteins in mammalian cell lines. To optimize the protein production platform, the roles of Ubiquitous Chromatin Opening Element (UCOE), an insulator, and selected promoters were evaluated based on efficiency and stability of foreign gene expression mediated by lentiviral vecto...
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Transgenic animals can be broadly defined as animals that contain recombinant DNA molecules in their genome that have been introduced by human intervention (Wall, 1996). Developmental studies and clinically relevant disease models are based on transgenic laboratory animals, most commonly the mouse. In farm animals, transgenic technology is used to produce large quantities of pharmaceutically re...
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ژورنال
عنوان ژورنال: International Journal of Medical Sciences
سال: 2015
ISSN: 1449-1907
DOI: 10.7150/ijms.11270